| Position |
SCIENTIST 'B'
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| Affiliation |
NATIONAL INSTITUTE FOR RESEARCH ON REPRODUCTIVE HEALTH (ICMR), MUMBAI
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| Location |
nan
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| Current Role |
Scientist
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| Area of Research |
We are currently investigating the role of Toll like receptors (TLR) family, which are an important class of PRRs, that play a role in activating the innate immune responses. The questions we are trying to address about TLRs in breast cancer is: (i) Whether TLR expression on cancer cells or non-cancer cells like immune cell/stromal cells/endothelial cells have different effects on growth of cancer tissue? (ii) Are TLR agonists/antagonists an effective strategy for enhancing cancer killing capacity of currently used chemotherapy drugs for breast cancer patients? In addition, we are looking at the association of placenta derived factors on promoting the initiation and development of breast cancer during pregnancy.
Also, the lab that I am apart of works on understanding different aspects of feto-maternal interactions. And my research interest involves in finding out factors contributing to bio-sensing ability of endometrial cells in response to good/bad quality embryos and its effect on recurrent implantation failures.
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| UG |
BIOPHYSICS-2002-PANJAB UNIVERSITY, CHANDIGARH
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| PG |
BIOPHYSICS-2004-PANJAB UNIVERSITY, CHANDIGARH
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| PhD |
2012-LIFE SCIENCE (CANCER GENETICS)-JADAVPUR UNIVERSITY, KOLKATA
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| Awards |
CSIR-RA FELLOWSHIP (2013)
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| Significant Contribution |
I am a cancer researcher. I currently gave two funded projects (ongoing). My current research aims to explore novel immunetherapy candidates to enhance clinical outcome in triple negative breast cancer patients. I have 23 publications to my credit in research focused on cancer biology and cancer genetics.
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| Bio |
I am a cancer biologist. I completed my PhD in 2012 and my research topic involved understanding the role of wnt signaling pathway alterations in breast cancer patients. I have worked as research associate and worked on characterizing the Wnt pathway alterations in er positive and triple negative breast cancers. I have worked as a postdoctoral scientist in breast cancer therapeutics division, national institute of cell biotechnology, Ireland. While working in this institute i got working experience in translational oncology and learnt how data obtained from research lab can be translated to clinical trials through proper evaluation and collaborations. In my current institute, at NIRRH, i work on understanding the role of toll like receptors in enhancing chemosensitivity of triple negative breast cancer patients. Also my research interests lie in looking at parameters regulating the biosensitivity of endometrial cells to developmentally competent/embryos.
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| Primary Role |
Research
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| Leadership |
I am a principle investigator in two ongoing funded projects
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| Twitter |
nan
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| Contact |
nupurmukherjee10@gmail.com
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